As people age beyond their reproductive prime, multiple shifts and changes occur that affect their sexual function and ability to procreate. For men, hormonal and metabolic changes can cause erectile dysfunction, reduced libido, loss of muscle mass, and changes in physical performance.
Nicotinamide adenine dinucleotide (NAD) is a key coenzyme found in every cell whose anti-aging properties help to preserve male reproductive health. Delivery via intravenous infusion (IV) is a fast and efficient way to boost the mechanisms that foster male fertility and reproductive health and enhance sexual performance.
Characteristics of Male Reproductive Aging
The human body is a dynamic organism that constantly changes from conception to death. Its ongoing evolution is driven by biological factors like hormones, growth factors and metabolic mechanisms like cellular neogenesis and energy production. Genetics plays a key role, with predetermined cellular chromosomal makeup governing male and female reproductive capabilities.
Both men and women achieve reproductive milestones at puberty and enjoy a couple decades of peak reproductive capacity before their internal clocks begin to shift into low gear. For women, the end of reproductive ability is often preceded by several years of telltale symptoms like irregular menses, hot flashes, sleep disturbance and mood swings, culminating in complete menopause. For men, reproductive decline is often more gradual and subtle.
Historically, measurable testosterone decline in men occurred around the age of 40, but over the past two decades, research is showing an alarming drop in testosterone levels in teens and young men. At the same time, more men are delaying fatherhood, choosing to start a family after their reproductive capacity has peaked. The CDC has reported a historic decline in birth rate in the US over the past decade, with fertility declining at the rate of about 2% per year since 2014.
For many men, reduced libido and loss of erectile function can lead to depression and anxiety. However, according to recent research, at least 90% of erectile dysfunction is associated with metabolic conditions unrelated to aging, Hypertension, diabetes and chronic systemic inflammation affect the circulatory system, restricting adequate blood flow to the male genitalia. Medications used to treat metabolic disorders can further impede reproductive function and reduce male fertility.
How NAD Boosts Male Reproductive Health
Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in every human cell. Your body produces NAD from certain nutrients, but NAD levels begin to decline as you age, creating a deficit that affects cellular function and performance.
NAD slows the aging process by:
- Boosting testosterone production
- Enhancing muscle function
- Reducing insulin resistance
- Enhancing energy metabolism
- Protecting cellular mitochondria
- Enhancing DNA repair
- Increasing basal metabolism
- Improving sleep quality
- Promoting longevity
Male reproduction has multiple NAD-dependent functions. As NAD levels naturally decline, men may be faced with reduced sexual performance, lower sperm count and reduced sperm genetic integrity, which in turn affects the health of the offspring of older men.
Multiple lifestyle factors play a role in the rate of NAD and testosterone decline. There are many lifestyle changes you can make to optimize NAD and testosterone levels and slow the aging process.
Lifestyle factors that support NAD production and boost testosterone include:
- Achieving and maintaining a healthy body weight
- Adopting a whole foods diet rich in animal protein and nutrient-dense plant sources
- Optimizing hydration and electrolyte levels
- Regular resistance training to boost lean muscle mass and mitochondria
- Cardiovascular exercise to enhance circulatory health
- Stress management and consistent sleep habits
Healthy lifestyle habits dramatically reduce your risk of metabolic disorders like hypertension, diabetes and systemic inflammation that accelerate aging and reduce reproductive performance.
Nutrients that Boost NAD Production
Supplementing with NAD precursors can boost NAD production and promote men’s health. Precursors are nutrients that your body uses to manufacture NAD.
NAD precursors include:
- Tryptophan (TRP)
- Nicotinic Acid (NA)
- Nicotinamide (NAM)
- Nicotinamide Riboside (NR)
- Dihydronicotinamide Riboside (NR)
Foods rich in Vitamin B3, aka niacin, provide a highly usable precursor that supports NAD production. Liver, grass-fed beef, bone broth, chicken, turkey and cold water fish are all good sources of B3. Not only do those foods support NAD production, but they help to boost testosterone levels as well. However, it may be difficult to get ample amounts of B3 from your diet alone to offset naturally declining NAD levels.
There is a broad range of dietary supplements on the market that can help boost NAD levels. When combined with other healthy lifestyle changes, NAD supplements can give your body the nutrients it needs to optimize reproductive health. However, the quality and absorbability of supplements varies from one product to the next, and even a high-quality supplement can lose its potency during the digestive process.
NAD IV therapy bypasses your digestive system and delivers potent NAD precursors directly to your bloodstream via intravenous infusion. Once it enters your circulatory system, the supplement is quickly distributed among NAD-depleted cells without the risk of losing potency. IV therapy is a fast and effective way to boost NAD production and leverage its benefits for reproductive health.
NAD IV Therapy at Invita Wellness in NYC
Male reproductive health and fertility is highly dependent on lifestyle factors that help you maintain virility and boost sexual performance. Nutrient supplementation via IV infusion can help you improve your NAD and testosterone levels and slow the aging process.
NAD IV therapy is one of many therapeutic services offered at Invita Wellness that help you optimize your health, promote longevity, and enhance your quality of life. Contact Invita Wellness today and take charge of your health so you can enjoy life to its fullest!
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Resources
Bhasin, Shalender, Rodrigo J. Valderrábano, and Thiago Gagliano-Jucá. “Age-related changes in the male reproductive system.” Endotext [Internet] (2022).
https://medlineplus.gov/ency/article/004017
Feng, Yan-Qin, et al. “NAD+ precursors promote the restoration of spermatogenesis in busulfan-treated mice through inhibiting Sirt2-regulated ferroptosis.” Theranostics 14.6 (2024): 2622.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11024856/
Feuz, Morgan B., et al. “Reproductive Ageing: Current insights and a potential role of NAD in the reproductive health of aging fathers and their children.” Reproduction 167.6 (2024).
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Lokeshwar, Soum D., et al. “Decline in serum testosterone levels among adolescent and young adult men in the USA.” European urology focus 7.4 (2021): 886-889.
https://pubmed.ncbi.nlm.nih.gov/32081788/