NAD+ IV therapy at InVita Wellness delivers nicotinamide adenine dinucleotide (NAD+) directly into your bloodstream through a slow, monitored drip at our clinic at 456 Broadway in SoHo, Manhattan. NAD+ is a coenzyme your cells rely on to produce energy, maintain healthy mitochondria, and repair DNA (Nature Reviews Molecular Cell Biology, 2021). NAD+ in some tissues declines with age (PLoS One, 2012), which is why many New Yorkers turn to NAD+ treatment when low energy, slower recovery, or brain fog become harder to shake.
Before your first treatment, a good faith exam is required to determine whether you qualify, followed by a consultation with an infusion specialist about your goals, options and an appropriate dose. Our infusion team then sets up your IV, and a session takes from about 20 minutes to about 2.5 hours, depending on your dose and individual tolerance. Doses range from 75 mg to 750 mg, given on their own or combined with nutrients such as resveratrol, curcumin, or CoQ10, following standing orders and approved protocols, with a qualified registered nurse supervising every infusion.
NAD+ IV at a glance
| What it is | NAD+, a coenzyme found in every cell, given by slow intravenous drip |
|---|---|
| Doses we offer | 75 mg, 250 mg, 500 mg or 750 mg |
| Time in the chair | About 20 minutes (75 mg) to about 150 minutes (750 mg); times vary with individual tolerance, and we give you an estimate when you book |
| Price | From $100 for a 75 mg base drip; signature NAD+ drips $650 to $800 per session, packages save 20 to 25% |
| Who supervises the drip | A qualified registered nurse supervises every infusion. Care is physician-guided and RN-led, following standing orders and approved protocols |
| Before your first drip | A good faith exam to determine whether you qualify, then a consultation with an infusion specialist about your goals, options and an appropriate dose |
| Where the NAD+ comes from | Licensed pharmacies. We disclose the source, and a certificate of analysis (COA) is available upon request |
| Not suitable for | Pregnancy and breastfeeding, active cancer, G6PD deficiency and several other conditions. See the full list |
Why Your Body May Need NAD⁺ Support
- Physical Fatigue – persistent low energy or reduced physical stamina
- Slower Recovery – longer bounce-back after exercise, illness, or long workdays
- Mental Fog – difficulty focusing, slowed thinking, or reduced clarity
- Plateaued Results – supplements and lifestyle changes no longer feel effective
- Chronic Stress – ongoing burnout that doesn’t fully resolve with rest
- Long-Term Resilience – a proactive focus on cognitive function and healthy aging
How Do I Know If NAD+ Therapy Is Right for Me?
Benefits of NAD+ IV Therapy
NAD+ helps cells turn food into energy and supports mitochondria, the tiny structures inside each cell where energy is produced.
Supplementation with NAD+ via IV infusion is a direct way to deliver NAD+ to your bloodstream. Blood NAD+ rises gradually over the course of a slow infusion (Frontiers in Aging Neuroscience, 2019). Individual experiences vary.
What the Research Says
NAD+ is an active and growing research area. Here is a short overview; individual experiences vary.
- NAD+ is essential for cellular energy and repair, and it is one of the most closely studied molecules in healthy-aging research (Nature Metabolism, 2025).
- Studies of IV NAD+ show that a slow infusion raises NAD+ levels in the blood (Frontiers in Aging Neuroscience, 2019). Research on longer-term effects is still developing (Frontiers in Aging, 2026).
- Many clients tell us they feel more energized and focused after their sessions. Experiences differ from person to person.
- We offer NAD+ IV as part of a wellness and healthy-aging program, not as a replacement for medical care.
Key Advantages of NAD+ IV Therapy
- Prolong Your Healthspan: Designed for those who want to maximize their “vibrant years” and maintain long-term vitality.
- Combat Age-Related Decline: NAD+ levels in some tissues tend to decrease with age (PLoS One, 2012).
- Physician-Guided, RN-Led: Every infusion follows standing orders and approved protocols. Before your first treatment, a good faith exam is required to determine whether you qualify.
- Safe Integration: If you are currently being treated for a pre-existing condition, we recommend consulting your physician before starting
Learn how NAD+ therapy works:
What to Expect on Your First Visit
At Invita Wellness, we pull out all the stops to ensure that your visit is safe, pleasant and relaxing. Our spa-like clinic is designed to put you at ease as your IV solution is delivered.
A good faith exam determines whether you qualify, followed by a consultation with an infusion specialist about your goals, options and an appropriate dose.
We set you up for your infusion session and prepare your IV.
Session length depends on your dose, from about 20 minutes to about 2.5 hours. Once the infusion begins, you can sit back and relax: read, scan social media, work online, or even take a nap.
A qualified registered nurse supervises your infusion, making sure you are comfortable and your drip is progressing.
Once your IV session has run its course, we make sure the infusion site is disinfected and you are ready to return to your daily routine.
How Long Does an NAD+ IV Take?
NAD+ is infused slowly, so a higher dose means more time in the chair. The times below are approximate and can vary with individual tolerance; we give you an estimate when you book.
| NAD+ dose | Approximate time | Base price |
|---|---|---|
| 75 mg | About 20 minutes | $100 |
| 250 mg | About 90 minutes | $300 |
| 500 mg | About 120 minutes | $600 |
| 750 mg | About 150 minutes | $800 |
Base price for NAD+ only. Boosters and add-ons are priced separately. Prices updated November 2026.
Enjoy Noticeable Effects After Your NAD+ IV Session
The effects of NAD IV therapy can vary significantly from one individual to the next. Some people report immediate effects during or right after the session, although more therapeutic benefits typically build over time.
Some clients notice a lift in energy and mental clarity as the IV finishes. Blood NAD levels will continue to increase before they peak over the next several hours (Frontiers in Aging Neuroscience, 2019).
Many clients describe feeling less tired and more focused in the days that follow. Some feel temporarily tired for a day or two as the body adjusts.
Over the following weeks, clients often describe steadier energy and better sleep. How long you feel the effects and how often you return is individual; your infusion specialist will suggest a schedule based on your response and our protocols.
Optimize the Benefits of NAD+ IV Therapy
- Resveratrol
- NAD (500 mg)
- Vitamin Drip (B-complex, B12, Electrolytes, Amino Acids, Vitamin C)
- Curcumin
- NAD (500 mg)
- Vitamin Drip (B-complex, B12, Electrolytes, Amino Acids, Vitamin C)
- Taurine, CoQ 10
- NAD (500 mg)
- Vitamin Drip (B-complex, B12, Electrolytes, Amino Acids, Vitamin C)
Choose Your NAD+ Therapy Plan
We’re located: 456 Broadway 2 Floor, New York · Prices updated November 2026
NAD+
AGELESS DRIP
5-10 treatments – 1-2 per week
This unique and simple drip will help you stay hydrated, increase energy, metabolism
SINGLE SESSION
$650
Pack of 5
$2,600 (20%)
Pack of 10
$4,875 (25%)
NAD+ OPTIMAL
IMMUNITY
6 treatments – once a week
NAD+ activates SIRT’s that decrease inflammation, extends cell life and speeds up metabolism.
SINGLE SESSION
$700
Pack of 6
$3,350 (20%)
NAD+
Cellular Detox
8 treatments – twice a week
NAD+ improves cognitive function and mental clarity.
SINGLE SESSION
$800
Pack of 8
$4,800 (25%)
NAD+
Optimal Longevity:
Unlock the secrets of longevity with our Optimal Longevity IV Drip. Infused with NAD, Resveratrol, and vital vitamins, this blend revitalizes your body at the cellular level, promoting longevity and enhancing overall well-being.
SINGLE SESSION
$700
NAD+ Optimal
Energy
Elevate your energy levels to new heights with our Optimal Energy IV Drip. Formulated with NAD, Taurine, CoQ10, and essential vitamins, this infusion provides a powerful boost of energy, revitalizing your body and enhancing your vitality.
SINGLE SESSION
$700
Create your
own
Just follow 3 simple steps to Optimal Wellness:
Not sure which plan is right for you?
Get Safe and Effective NAD+ Infusions in NYC's Trendy SoHo
InVita Wellness has offered NAD+ IV therapy in SoHo since 2016 and gives more than 1,200 NAD+ infusions a year. NAD+ products vary widely in quality, potency, and safety, so we source NAD+ from licensed pharmacies. We disclose the source, and a certificate of analysis (COA) is available upon request.
InVita Wellness is located at 456 Broadway, 2nd Floor, in SoHo, a short walk from the Canal Street subway station (N, Q, R, W, J, Z and 6 lines). That makes our clinic an easy trip for NAD+ IV therapy from anywhere in Manhattan, Brooklyn, and Queens. It is equally convenient for clients coming from New Jersey through the Holland Tunnel or for commuters from Westchester arriving at Grand Central.
How to Choose an NAD+ IV Provider in NYC
NAD+ is offered everywhere from medical clinics to mobile IV services. These are the questions worth asking before you book, and how we answer them:
- Who guides the protocols? Our care is physician-guided and RN-led; every infusion follows standing orders and approved protocols. See our team
- Who supervises the drip? A qualified registered nurse, throughout the infusion
- Is there a check before the first drip? Yes, a good faith exam to determine whether you qualify
- Where does the NAD+ come from? Licensed pharmacies; we disclose the source, and a COA is available on request
- Are prices clear before you book? Yes, every plan is listed on this page
- Are expectations honest? We do not promise to treat or cure any condition
Experienced Care. Personally Led.
The people who founded InVita in 2016 still lead it today. Their experience, standards and personal involvement continue to shape the client experience.
An anesthesiologist with more than 25 years of experience, Dr. Shapiro oversees InVita’s protocols and the standards behind each recommendation.
A registered nurse for more than 30 years, much of that time at Beth Israel Medical Center, Inessa has led InVita’s IV and NAD+ therapies since its founding in 2016. She brings expertise, warmth and continuity to every client relationship.
FAQ
NAD+ sessions and cost
How long does an NAD+ IV session take?
Approximately 20 minutes for 75 mg, 90 minutes for 250 mg, 120 minutes for 500 mg and 150 minutes for 750 mg. Times can vary with individual tolerance, and we give you an estimate when you book.
How much does NAD+ IV therapy cost in NYC?
At InVita Wellness, a 75 mg NAD+ base drip starts at $100; 250 mg is $300, 500 mg is $600 and 750 mg is $800. Signature NAD+ drips that combine NAD+ with vitamins and cryotherapy or infrared therapy are $650 to $800 per session, and packages save 20 to 25%. Boosters and add-ons are priced separately.
Is NAD+ IV therapy worth it?
Many clients choose NAD+ IV as part of their energy and healthy-aging routine, and experiences vary from person to person. Research on IV NAD+ is still developing, so we talk through your goals and expectations at your consultation and suggest a plan that fits them.
How often should I get NAD+ infusions?
Frequency is individual. Your infusion specialist suggests a schedule based on your goals, how you respond to your sessions and our approved protocols, and adjusts it over time.
What happens before my first NAD+ drip?
Before your first treatment, a good faith exam is required to determine whether you qualify. This is followed by a consultation with an infusion specialist to discuss your goals, options and an appropriate dose. Every infusion follows standing orders and approved protocols.
What is an NAD+ therapy session like?
You relax in a comfortable chair while NAD+ is infused slowly through an IV. A qualified registered nurse supervises your infusion and can adjust the drip speed to keep you comfortable. Many clients read, work on a laptop or rest during the session.
How do you determine the best NAD+ treatment plan?
Your plan is based on your good faith exam, your goals and how you tolerate NAD+. Your infusion specialist suggests a dose and, if you wish, add-ons such as resveratrol, curcumin or CoQ10, all within our approved protocols.
NAD+ safety and science
What are the side effects of NAD+ IV therapy?
During the drip, some people feel chest tightness or pressure, nausea, flushing, stomach cramping or a headache. These sensations are usually linked to how fast NAD+ is infused and ease when the drip is slowed (Frontiers in Aging, 2026). Some clients feel tired for a day or two after a session. Tell your nurse right away if anything feels unusual.
Why can NAD+ cause chest tightness or nausea during the drip?
When NAD+ enters the bloodstream too quickly, the body can respond with pressure in the chest, nausea or flushing. That is why NAD+ is infused slowly and why your nurse adjusts the rate to how you feel; the sensations usually fade once the drip is slowed.
Who should not get NAD+ IV therapy?
NAD+ IV therapy is not suitable for people who are pregnant or breastfeeding, have active cancer, G6PD deficiency, advanced liver, kidney or cardiovascular disease, advanced Parkinson’s disease treated with high-dose levodopa, or who take SSRIs or antipsychotic medications. Your good faith exam determines whether NAD+ IV is right for you.
Does NAD+ help with weight loss?
NAD+ IV therapy is not a weight-loss treatment. NAD+ plays a role in how cells turn food into energy, and research on its effects on metabolism is ongoing, but we do not offer it as a way to lose weight.
What is the best age to begin NAD+ therapy?
There is no single best age. Most clients start NAD+ IV in adulthood as part of an energy or healthy-aging routine, and your good faith exam and consultation help decide whether it suits you.
How does NAD+ work at the cellular level?
NAD+ is a coenzyme found in every cell. It helps turn food into energy in the mitochondria, and it is used by enzymes called sirtuins and PARPs, which are involved in cell maintenance and DNA repair (Nature Reviews Molecular Cell Biology, 2021).
Research and Therapeutic Uses
https://www.nature.com/articles/s44324-025-00067-0 – 2025.
https://doi.org/10.1038/s42255-025-01387-7 – 2025.
https://doi.org/10.1371/journal.pone.0042357 – 2012.
https://pubmed.ncbi.nlm.nih.gov/27304511/ – 2016.
https://doi.org/10.1038/s41580-020-00313-x – 2021.
https://doi.org/10.3389/fnagi.2019.00257 – 2019.
https://doi.org/10.3389/fragi.2026.1652582 – 2026.
https://doi.org/10.1038/s41467-018-03421-7 – 2018.
https://doi.org/10.1126/science.abe9985 – 2021.
https://doi.org/10.1038/s42255-026-01537-5 – 2026.
https://doi.org/10.3389/fragi.2026.1887175 – 2026.
https://doi.org/10.1002/jcsm.13799 – 2025.
https://www.sciencedirect.com/science/article/am/pii/S0006291X24001256 – 2024.
https://www.sciencedirect.com/science/article/abs/pii/S0026049521002237 – 2022.
https://pubmed.ncbi.nlm.nih.gov/27304496/ – 2016.
https://doi.org/10.3390/ph13090247 – 2020.
https://journals.sagepub.com/doi/abs/10.1177/1535370220929287 – 2020.
Visit InVita Wellness in SoHo
| Address | 456 Broadway, 2nd Floor, New York, NY 10013 |
|---|---|
| Phone | +1 (646) 998 4952 |
| Hours | Tuesday to Friday 10 am to 7 pm · Saturday 10 am to 4 pm · Sunday and Monday closed |
| Subway | Canal St (N, Q, R, W, J, Z, 6), a short walk |
| Same-day appointments | Available, subject to availability |
