Coenzymes are molecules derived from food sources that are vital to human health. The role of coenzymes is so important that they are often used as nutraceuticals to treat various medical conditions. Two important coenzymes backed by large volumes of scientific evidence are nicotinamide adenine dinucleotide (NAD+) and coenzyme Q10 (CoQ10).
Learn about the actions of NAD+ and CoQ10, their benefits for human health, and how delivery via IV therapy is a safe and effective way to optimize their effectiveness.
What are Coenzymes and How Do they Affect Cellular Health?
Coenzymes are organic molecules that bind to enzymes to assist in chemical reactions in the cells. They often function as intermediate carriers of electrons during chemical reactions, or they can be transferred between enzymes. Some coenzymes like NAD+ and CoQ10 are vital to human life.
Coenzymes are derived from certain vitamins and play an important role in enzyme activities, such as the synthesis of adenosine triphosphate (ATP), the energy molecule. Many coenzymes are fundamental components of all living cells, and some – such as glutathione and CoQ10 – function as antioxidants to fight against free radicals that harm cellular health.
Two important coenzymes derived from common food sources that play vital roles in every living cell are Coenzyme Q10 and nicotinamide adenine dinucleotide. Both are known to protect your mitochondria, support and repair DNA, and shield your cells from the adverse effects of aging.
NAD+ and CoQ10 Benefits
Coenzyme Q10 (CoQ10)
CoQ10 is a crucial component in the mitochondrial electron transport chain – the cascade of chemical reactions that produce ATP, the energy molecule. CoQ10 is sometimes called by its reduced form, ubiquinol. CoQ10 plays a crucial role as an antioxidant for cellular membranes and lipoproteins, protecting them from oxidative damage. CoQ10 repairs oxidative damage via direct interaction with reparative DNA enzymes.
Nicotinamide Adenine Dinucleotide (NAD+)
NAD+ is the biologically functional form of nicotinamide adenine dinucleotide. Its state is modified when it receives electrons that transform it into NADH (NAD + hydrogen (H)). Like coenzyme Q10, NAD+ plays a critical role in mitochondrial health and ATP metabolism.
NAD+ and CoQ10: Your Cellular Health Dream Team
Your body naturally produces NAD+ and CoQ10 from dietary sources. However, NAD levels decline as you age. Exercise is one of the best ways to promote NAD+ production. Intermittent fasting and ketogenic diets also encourage the synthesis of NAD. Statin drugs prescribed to target cholesterol rapidly deplete CoQ10 levels and reduce the number of mitochondria in muscle cells.
Modern diets rarely provide all the nutrients you need for optimal health. CoQ10 is most abundant in chlorophyll-rich greens, fatty cold-water fish like salmon and sardines, and organ meats like beef liver. Abundant sources of NAD include beef, pork, turkey, fatty fish and dairy. Vegan and vegetarian diets, or diets that exclude fish and organ meats may be insufficient to meet your dietary needs for CoQ10 and NAD+.
In addition to making positive lifestyle changes with diet and exercise, you should consider supplementing with coenzyme Q10 and NAD for mitochondrial health, and as a deterrent to metabolic dysfunction and age-related diseases. Regular infusions with NAD+ and CoQ10 IV therapy is a safe and effective way to boost your levels of these vital coenzymes for better health and longevity.
Protect Your Health with NAD+ and CoQ10 IV Therapy in NYC
Getting all the nutrients you need from diet alone is a challenge in the 21st century. High-stress lifestyles, fast and processed foods and vegetarian diets can leave your cells depleted of essential enzymes necessary for cellular health.
Protect Your Health with NAD+ and CoQ10
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Resources
Ahmadi, Armin, et al. “Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease.” JCI insight 8.11 (2023).
Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease
Aaseth, Jan, Jan Alexander, and Urban Alehagen. “Coenzyme Q10 supplementation–In ageing and disease.” Mechanisms of Ageing and Development 197 (2021): 111521.
https://www.sciencedirect.com/science/article/pii/S0047637421000932
Barcelos, Isabella Peixoto de, and Richard H. Haas. “CoQ10 and aging.” Biology 8.2 (2019): 28.
CoQ10 and aging
Chini, Claudia CS, Mariana G. Tarragó, and Eduardo N. Chini. “NAD and the aging process: Role in life, death and everything in between.” Molecular and cellular endocrinology 455 (2017): 62-74.
https://www.sciencedirect.com/science/article/abs/pii/S0303720716304622
Díaz-Casado, M. Elena, et al. “The paradox of coenzyme Q10 in aging.” Nutrients 11.9 (2019): 2221.
The Paradox of Coenzyme Q10 in Aging
